Official ABC synopsis
A primetime soap with a truly contemporary take on the "happily ever after," "Desperate Housewives" takes a darkly comedic look at suburbia, where the secret lives of housewives aren't always what they seem.

Season 1:
1-1 Pilot (10.03.04)
1-2 Ah, But Underneath (10.10.04)
1-3 Pretty Little Picture (10.17.04)
1-4 Who’s That Woman (10.24.04)
1-5 Come in Stranger (10.31.04)
1-6 Running to Stand Still (11.07.04)
1-7 Anything You Can Do (11.21.04)
1-8 Guilty (11.28.04)
1-9 Suspicious Minds (12.12.04)
1-10 Come Back to Me (12.19.04)
1-11 Move On (1.09.05)
1-12 Every Day a Little Death (1.16.05)
1-13 Your Fault (1.23.05)
1-14 Love is in the Air (2.13.05)
1-15 Impossible (2.20.05)
1-16 The Ladies Who Lunch (3.27.05)
1-17 There Won’t Be Trumpets (4.03.05)
1-18 Children Will Listen (4.10.05)
1-19 Live Alone and Like It (4.17.05)
1-20 Fear No More (5.01.05)
1-21 Sunday in the Park with George (5.08.05)
1-22 Goodbye For Now (5.15.05)
1-23 One Wonderful Day (5.22.05)

Season 1 Mystery
The big mystery was why Mary Alice Young shot herself in the head. Turns out she killed herself because she felt so guilty over killing Deirdre, the ex-junkie and true mother of Zach.

Season 2
2-1 Next (09.25.05)
2-2 You Could Drive A Person Crazy (10.02.05)
2-3 You’ll Never Get Away From Me (10.09.05)
2-4 My Heart Belongs to Daddy (10.16.05)
2-5 They Asked Me Why I Believed in You? (10.23.05)
2-6 I Wish I Could Forget You (11.06.05)
2-7 Color and Light (11.13.05)
2-8 The Sun Won’t Set (11.20.05)
2-9 That’s Good, That’s Bad (11.27.05)
2-10 Coming Home (12.04.05)
2-11 One More Kiss (01.08.06)
2-12 We’re Gonna Be All right (01.15.06)
2-13 There’s Something About a War (01.15.06)
2-14 Silly People (01.22.06)
2-15 Thank You So Much (2.19.06)
2-16 There is No Other Way (03.12.06)
2-17 Could I Leave You? (03.26.06)
2-18 Everybody Says Don’t (04.02.06)
2-19 Don’t Look At Me (04.16.06)
2-20 It Wasn’t Meant to Happen (04.30.06)
2-21 I Know Things Now (05.07.06)
2-22 No One is Alone (05.14.06)
2-23 Remember (05.14.06)

Season 2 Mystery
The mystery was twofold: Why did Betty Applewhite kept her son, Caleb, locked up in the basement? And will George ever be uncovered as the murdering pharmacist who bumped off Rex?

Season 3
3-1 Listen to the Rain on the Roof (09.24.06)
3-2 It Takes Two (10.01.06)
3-3 A Weekend in the Country (10.08.06)
3-4 Like It Was (10.15.06)
3-5 Nice She Ain't (10.22.06)
3-6 Sweetheart, I have to Confess (10.29.06)
3-7 Bang (11.05.2006)
3-8 Children and Art (11.12.06)
3-9 Beautiful Girls (11.19.06)
3-10 The Miracle Song (11.26.06)
3-11 No Fits, No Fights, No Feuds (01.07.07)
3-12 Not While I'm Around (01.14.07)
3-13 Come Play Wiz Me (01.21.07)
3-14 I Remember That (02.11.07)
3-15 The Little Things You Do Together (02.18.07)
3-16 My Husband the Pig (03.04.07)
3-17 Dress Big (04.08.07)
3-18 Liaisons (04.15.07)
3-19 God, That's Good (04.22.07)
3-20 Gossip (04.29.07)
3-21 Into the Woods (05.06.07)
3-22 What Would We Do Without You? (05.13.07)
3-23 Getting Married Today (05.13.07)

Season 4
4-1 "Now You Know" (09.30.07)
4-2 "Smiles of a Summer Night" (10.07.07)
4-3 "The Game" (10.14.07)
4-4 "If There's Anything I Can't Stand" (10.21.07)
4-5 "Art Isn't Easy" (10.28.07)
4-6 "Now I Know, Don't Be Scared" (11.04.07)
4-7 "You Can't Judge A Book By Its Cover" (11.11.07)
4-8 "Distant Past" (11.25.07)
4-9 "Something's Coming" (12.02.07)
4-10 "Welcome to Kanagawa" (01.06.08)
4-11 "Sunday" (04.13.08)
4-12 "In Buddy's Eyes" (04.20.08)
4-13 "Hello, Little Girl" (04.27.08)
4-14 "Opening Doors" (05.04.08)
4-15 "Mother Said" (05.11.08)
4-16 "The Gun Song" (05.18.08)
4-17 "Free" (05.18.08)

Susan Mayer (Teri Hatcher)
Lynette Scavo (Felicity Huffman)
Bree Hodge (Marcia Cross)
Gabrielle Solis (Eva Longoria Parker)
Edie Britt (Nicollette Sheridan)
Carlos Solis (Ricardo Chavira)
Mary Alice Young (Brenda Strong)
Mike Delfino (James Denton)
Julie Mayer (Andrea Bowen)
Porter Scavo (Shane Kinsman)
Preston Scavo (Brent Kinsman)
Tom Scavo (Doug Savant)
Parker Scavo (Zane Huett)
Danielle Van De Kamp (Joy Lauren)
Andrew Van De Kamp (Shawn Pyfrom)
Orson Hodge (Kyle MacLachlan)
Zach Young (Cody Kasch)
Paul Young (Mark Moses)

Rex's Secret
Back before he died of heart-pill-prescription tampering, Rex's big secret was that he was secretly in to S&M.